LAST UPDATED JAN 21, 2026
/hrt/feminizing/estradiol-oral

Estradiol (Oral)

[estradiol]
Rev: 2025.12
Summary
An oral form of Estradiol, commonly used by those with a fear of needles.

DESCRIPTION

Oral estradiol is a bioidentical form of the primary female sex hormone estrogen, typically administered as estradiol hemihydrate or estradiol valerate tablets.

DOSING GUIDELINES

RouteDose RangeFrequencyTarget Levels
Oral / Sublingual/Buccal2mg8mgDaily100-300pg/mL

DETAILED NOTES

Oral / Sublingual/Buccal

2mg-6mg must be taken with an anti-androgen, monotherapy levels (8mg daily) do not need an anti-androgen to suppress testosterone.

WHERE TO BUY

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Rev: 2025.12hrt.fm